the continuum of diabetic coma

The management of diabetic coma.

The "third coma" in diabetes: diabetic coma without ketoacidosis.

THE COMPLEXITIES of the diabetic syndrome are underlined by the fact that diabetic coma may occur without obvious ketoacidosis. The position has recently been summarised in a leading article in the British Medical Journal (1965). To the first two comas met with in diabetes, namely diabetic coma with ketosis and hypoglycaemic coma due to excess insulin, must then be added a third type of coma. T...

Reinterpretation of hyperamylasemia in diabetic coma.

Serum enzyme activity was sequentially determined in 10 consecutive patients with diabetic ketoacidosis, of whom all had increased -glucuronidase activity, eight had increased amylase activity, and four had increased acid phosphatase activity. Activity of amylase and that of the two lysosomal enzymes were poorly correlated, irrespective of whether peak activities or activities of all samples we...

A Case of Diabetic Coma with Lipæmia

consists of two cases mentioned by Dr Gamgee, and one by Dr Foster of Birmingham, which do not altogether support the theory, and of a case published by Dr Starr of Philadelphia, in which, on the other hand, the theory is amply confirmed by the demonstration of post-mortem appearances very closely resembling those described by Sanders and Hamilton. The statement of Dr Babbington in 1836, that t...

Hyperosmolar non-ketotic diabetic coma and rhabdomyolysis.

Rhabdomyolysis is a rare but potentially fatal complication of hyperosmolar states. We report a case of severe hyperosmolar non-ketotic diabetic coma causing rhabdomyolysis in a young man. Despite very high levels of creatine kinase there was no detectable myoglobinuria. Creatine kinase estimation should be a standard investigation in all patients presenting with a hyperosmolar state.

Low Dose Insulin Regimen for Diabetic Coma

Introduction Low dosage insulin regimens for diabetic "comas" have recently attracted considerable attention (Alberti, Hockaday and Turner, 1973; Page et al, 1974; Kidson et al, 1974; Semple, White and Manderson, 1974). These regimans have all originated from established diabetic centres, however the simplicity of these regimens, especially the intra muscular regimen (Alberti et al, 1973), woul...